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studies have suggested that patients with Barrett's oesophagus may be at increased risk of colorectal neoplasia, though the association is disputed. In a multicentre prospective study we compared the prevalence of colorectal adenomas in patients with Barrett's oesophagus and controls. The controls were patients with symptoms suggesting irritable bowel syndrome.
No participant had a personal history of colonic neoplasm. Each patient underwent colonoscopy.
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Three colorectal cancers were discovered in each group. The relative risk of adenoma was ificantly higher in patients older than 59 than in younger patients 2. Other factors contributing ificantly to the risk of adenoma were a family history of colorectal cancer 2.
We conclude that Barrett's oesophagus is not an independent risk factor for colorectal neoplasia and, therefore, is not, in itself an indication for colorectal screening. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.
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Abstract studies have suggested that patients with Barrett's oesophagus may be at increased risk of colorectal neoplasia, though the association is disputed. Comment in Barrett's oesophagus and colorectal carcinoma. Morgan G. PMID: No abstract available. Similar articles Barrett's oesophagus is not a risk factor for colonic neoplasia: a case-control study.
Laitakari R, et al. Ann Med. PMID: The prevalence of colonic neoplasia in patients with Barrett's esophagus: prospective assessment in patients years old. Poorman JC, et al.
Am J Gastroenterol. Colorectal neoplasms and Barrett's esophagus. Tripp MR, et al.
Review article: prevalence of Barrett's oesophagus and metaplasia at the gastro-oesophageal junction. Sharma P. Aliment Pharmacol Ther.
PMID: Review. Should patients with Barrett's oesophagus be kept under surveillance?
Multicentre prospective controlled study of barrett's oesophagus and colorectal adenomas. groupe d'etude de l'oesophage de barrett
The case against. Barritt AS 4th, et al. Best Pract Res Clin Gastroenterol. See all similar articles. Cited by 6 articles Current animal models of bladder cancer: Awareness of translatability Review.
Ding J, et al. Exp Ther Med. Epub Jul Higher prevalence of colon polyps in patients with Barrett's esophagus: a case-control study. Kumaravel A, et al. Gastroenterol Rep Oxf. Leers JM, et al. PMID: German.
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Demographic and phenotypic features of 70 families segregating Barrett's oesophagus and oesophageal adenocarcinoma. Drovdlic CM, et al. J Med Genet. No association between colon cancer and adenocarcinoma of the oesophagus in a population based cohort study in Sweden.
Lagergren J, Nyren O. Lagergren J, et al. See all "Cited by" articles. Publication types Clinical Trial Actions. Controlled Clinical Trial Actions. Multicenter Study Actions.
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